New-Generation Diabetes Drugs Review
Everyone who suffers from diabetes knows the types of 2 diabetes pills. But not every patient has heard about new drugs for treating this disease. The new generation anti-diabetic drug list contains different products. Ancora Pharmaceuticals will review the most popular treatment in this article.
Common anti-diabetic drugs
Doctors often prescribe Maninil, Diabeton, Gljurenorm, Amaryl. Each of these drugs has its own characteristics. They have the same function - to lower the level of sugar in the blood.
- Maninil is the most popular drug from the above list. It has a stimulating effect on the pancreas which begins to independently produce insulin in the right amount;
- Diabeton, stimulates the pancreas with beta cells. But its effect is slightly weaker than that of Maninil, although, under its influence, insulin is produced in a more natural way;
- Gljurenorm is used in cases where a patient who suffers from diabetes mellitus has other concomitant diseases. For example, kidney disorders. Usually, this medication is prescribed for the elderly;
- Amaril is a new generation drug. It stimulates the process of releasing insulin from the beta cells of the pancreas. This type of drug is often used in combination with insulin.
According to the WHO, 2 million people die from diabetes mellitus and its complications every year. In the absence of qualified body support, diabetes leads to various kinds of complications, gradually destroying the human body. Most common complications are diabetic gangrene, nephropathy, retinopathy, trophic ulcers, hypoglycemia, ketoacidosis. Diabetes can also lead to the development of cancerous tumors. In almost all cases, a diabetic person dies struggling with a painful illness or becomes a disabled person.
The variety of drugs that exists today allows doctors to maintain the health of patients with type 2 diabetes at the proper level. Of course, this requires adhering to the right diet and healthy lifestyle.
Characteristics of the disease
Everyone knows that diabetes mellitus type I and II is a disease that is associated with a metabolic disorder in the body. Therefore, all drugs that are prescribed to the patient, should normalize the metabolic process and "make" the body work independently. At the same time, the elderly and young patients can use different drugs.
The main cause of diabetes is the death of beta cells in the pancreas. These cells are responsible for the production of insulin. Accordingly, when the body lacks these cells, insulin must be administered by artificial means: with a special injection or an insulin pump.
But there is one nuance: if the stage of diabetes reached the point that the patient began to administer insulin, there is no alternative to the treatment of this disease. This is the so-called stage of type 1 diabetes mellitus.
Those who suffer from type 2 diabetes may use other drugs that are actively fighting the level of sugar in the blood and stimulate the body to produce insulin. Tablets that are used for diabetes mellitus can be divided into several appropriate categories.
At the same time, a medicine is not a panacea. Diabetes mellitus is an immune disease, so it is difficult for a patient to recover from this ailment. It is very important to lead a correct lifestyle, monitor your diet and fight overweight to avoid complex consequences.
In addition, any patient who suffers from type 2 diabetes mellitus should not forget that regular examination and preventive diabetes treatment should be performed on a regular basis in the medical institution.
Treatment of type 2 diabetes begins with a proper diet and increased physical loads. This rule is especially important in cases when the patient is overweight or the elderly. In this case, the goal of the diet is to normalize the weight and keep it in this state. The best diet for those who suffer from diabetes is a regular intake of healthy foods. Patients should exclude from the diet:
- refined carbohydrates (sugar, honey, jams, etc.);
- saturated fats;
- flour products and sweets;
The basis of nutrition are carbohydrates and those high-fiber foods. You can eat various fruits that are rich in fructose. As you know, fructose splits very well in the human body without the help of insulin.
It's allowed to eat buckwheat, rice and oatmeal.
And of course, a diabetic person should replace sugar with special sweeteners or honey.
Remember that compliance with the right diet for type 2 diabetes is very important for both treatment and prevention of this disease. Of course, taking drugs for diabetes is no less important in this matter. When taking medications, the patient should follow the exact dose, strictly control the time of intake and combine them with eating. Then it will be possible to maintain the health at the proper level and sometimes even completely normalize the work of the pancreas and other organs, which are responsible for the production of glucose in the blood.
Anti-diabetic drugs are divided into several classes. For example, in the early stages of the disease, a-glucosidase inhibitors are prescribed. They are also known as acarbose drugs. One of the acarbose-based medications is Precose - a drug in which a carbohydrate molecule is the key active ingredient. This product is manufactured by Ancora Pharmaceutical. This drug helps reduce the absorption of glucose into the intestinal wall. You can buy Precose online at Pharmacy Mall official site.
If it is necessary to actively stimulate the production of insulin in the body, a doctor prescribes sulfonylurea. This drug stimulates the production of insulin by the b-cells of the pancreas. But this type of drug is contraindicated if a person has the following complications:
- type 1 diabetes mellitus;
- pancreatic diabetes mellitus;
- period of pregnancy and breastfeeding;
- cavitary operations in the anamnesis;
- infectious diseases;
- possible injuries;
But when there is a sufficient amount of insulin in the patient's body, the endocrinologist prescribes medicines that belong to the biguanide group. This type of cure for diabetes does not affect the production of insulin but it works well for absorbing glucose in the intestine, thereby reducing the patient's appetite. But they are contraindicated to those people who suffer from kidney failure, have complications of diabetes mellitus and are in a hypoxic condition.
Often, all patients with diabetes mellitus do not feel anything special when the level of blood sugar changes. Although this process is quite dangerous and can lead to a number of negative consequences:
- a defeat of the heart;
- brain problems;
- eye diseases;
- renal insufficiency;
- problems associated with nerve endings;
- the damage to the structure of the vessels in the legs may.
But this is not the whole list of what can happen when blood sugar levels increase or decrease. Remember that any uncontrolled increase in glucose will lead to devastating consequences for the body.
Therefore, it is very important to take drugs that reduce blood sugar levels and contribute to the proper production of insulin. Although, long-term treatment with such drugs negatively affects the quality of blood, harms the stomach and liver.
Usually, an endocrinologist adjusts the dose of the anti-diabetic medicine based on a patient's physical condition. Therefore, those who suffer from diabetes should undergo an additional examination and visit their local endocrinologist on a regular basis. Also, they need to take the prescribed medicine strictly in accordance with the instructions and prescriptions of the doctor.
Choosing a treatment method
Only a doctor has the right to prescribe a drug for type 2 diabetes after a complete survey.
Tablets that are taken by patients with type 2 diabetes mellitus are divided into 4 categories:
- Sulfonylurea. This drug reduces the level of sugar by stimulating the pancreas, which begins to actively produce insulin. There are medicines of both the first and second generation. The first generation products include Dymelor, Diabinese, Orinase, Tolinase. But at the moment all these drugs are rarely used. Doctors most often prescribe tablets of a new generation: Glucotrol, Glucotrol XL, DiaBeta, Micronase, Glynase PresTab, Amaryl;
- Biguanides. This drug increases the ability of insulin to regulate the level of sugar in the cells. In addition, these tablets can block the release of sugar by the liver. But these drugs cannot be used for people who have complications in the work of the liver or heart. Otherwise, there may be a risk of developing lactic acidosis. This group includes the following new generation drugs: Biguanides, Glucophage, Riomet, Glucophage XR, Glumetza, Fortamet;
- Thiazolidinediones. These tablets help to reduce the level of insulin resistance. They affect the muscles and fat tissue. This group includes two drugs, namely Actos and Avandia. These are new generation drugs. But you need to take them with extreme caution. The level of sugar in the blood drops only after 1-2 weeks after the start of taking these drugs. At the same time, Avandia has a strong negative impact on the work of the cardiovascular system. Therefore, the use of this medication is not recommended for the elderly;
- Inhibitors of alpha-glucosidase. This group of drugs blocks the production of enzymes that break down starch and thereby slow the growth of blood sugar levels. In some cases, these products can cause diarrhea and strong gas formation. This list includes Precose and Glyset.
Of course, the choice of a drug depends on a number of factors. The final decision should always be taken by an attending physician.
Oral treatments to control blood sugar
In addition to all the above diabetes pills, there are other drugs that can reduce blood sugar levels:
- Meglitinides. This group includes Prandin and Starlix. These tablets have a stimulating effect on the pancreas, which begins to produce insulin in large quantities. But remember that these drugs are glucose-dependent, and their effect depends on the level of glucose in the blood.
- Dipeptidyl peptidase-4 inhibitors. These drugs include Januvia, Onglyza, Tradjenta. They reduce blood sugar in patients who suffer from type 2 diabetes. Their action is also aimed at increasing the secretion of insulin and simultaneously reducing blood glucose levels. They are used only in the cases when the patient has a significantly increased blood sugar. In addition, the level of sugar production by the liver decreases after their intake. These drugs are a new generation and they can be prescribed by a doctor as the main means or as an auxiliary medicine.
All these drugs are selected individually, taking into account the complexity of the course of the disease and the presence of concomitant diseases.